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Signs and Symptoms of Depression

“I don’t feel like myself anymore.”

 “Everything and everybody seems to bother me and I can’t feel happy.”

 “I feel like there’s this incredible weight on me and I’m dragging.”

 “It takes everything I have to get through the day. All I want to do is be alone or sleep.”

 “Everything I do takes so much effort.”

People with depression commonly express these kinds of feelings. Some people may not report a sad or depressed mood, but almost all complain they have a general sense of not being well that makes everyday activities and interactions burdensome.

Common signs and symptoms of depression include:

  • depressed mood, including feelings of guilt
  • “heavy weight” upon the person
  • constant tension, “always wound up”
  • frustration
  • irritability
  • frequent tearfulness and/or crying
  • lack of interest in any pleasurable activity—unable to feel pleasure or joy
  • poor self-esteem, “I don’t feel good about myself”
  • hopelessness
  • poor appetite
  • insomnia, with difficulty falling asleep and/or frequent middle-of-the-night awakening
  • dwelling on past events
  • constant fatigue or weariness
  • no improvement despite a positive change in the environment or events
  • difficulty with memory and concentration
  • withdrawal from friends and family
  • multiple physical complaints such as stomachache or headache that don’t get better with conventional treatment
  • thoughts of suicide

Experiencing five or more of these symptoms most days for two weeks characterizes major depression and indicates that someone should see a health professional.

Feeling a pervasive sense of sadness and agreeing with fewer than five of these categories may mean a person is suffering from either major depression or a milder form of depression and still may benefit from treatment.

By Josepha Cheong, MD; Michael Herkov, PhD; Wayne Goodman, MD
©1999-2004 University of Florida McKnight Brain Institute